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Pikatza-Menoio O, Elicegui A, Bengoetxea X et al (2021) The skeletal muscle emerges as a new disease target in amyotrophic lateral sclerosis

They suggest steering clear of non-prescription use

Thermal sensitivity testing demonstrated that as a group, at baseline, the subjects exhibited a reduction of function of cold detection threshold of all three regions tested, and reduced function in warm detection threshold in the foot and hand (Figure 7)

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In contrast, we found comparatively lower expression of the norepinephrine transporter (NET, SLC6A2 ) in -cells and -cells (Fig